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Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells
Nitazoxanide(NTZ) exhibits potent antiviral activity against hepatitis C virus (HCV) in cell culture. Previously, HCV replicon-containing cell lines resistant to NTZ were selected, but transfer the HCV NTZ-resistance phenotype was not observed following transfection of whole cell RNA. To further exp...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159803/ https://ncbi.nlm.nih.gov/pubmed/21703309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.05.017 |
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