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Potential for Hepatitis C Virus Resistance to Nitazoxanide or Tizoxanide
Nitazoxanide and its primary metabolite, tizoxanide, inhibit hepatitis C virus (HCV) replication in HCV replicon systems. To study the potential for resistance, we subjected Huh7 cells harboring HCV replicons to serial passage in 250 μM G418 and increasing concentrations of nitazoxanide or tizoxanid...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2573111/ https://ncbi.nlm.nih.gov/pubmed/18710916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00078-08 |
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