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HCV Replicon Systems: Workhorses of Drug Discovery and Resistance
The development of direct-acting antivirals (DAAs) has revolutionized the state-of-the art treatment of HCV infections, with sustained virologic response rates above 90%. However, viral variants harboring substitutions referred to as resistance-associated substitutions (RASs) may be present in basel...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2020-06-01
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Colecção: | Frontiers in Cellular and Infection Microbiology |
Assuntos: | |
Acesso em linha: | https://www.frontiersin.org/article/10.3389/fcimb.2020.00325/full |
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