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Bayesian Hierarchical Mixture Modelling to Assign Copy Number from a targeted CNV array

Accurate assignment of copy number at known copy number variant (CNV) loci is important for both increasing understanding of the structural evolution of genomes as well as for carrying out association studies of copy number with disease. As with calling SNP genotypes, the task can be framed as a clu...

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Detalhes bibliográficos
Main Authors: Cardin, Niall, Holmes, Chris, Donnelly, Peter, Marchini, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159791/
https://ncbi.nlm.nih.gov/pubmed/21769931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20604
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