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Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can cause oxidative damage to DNA, proteins, and membrane lipids. Glutathione peroxidase-1 (GPx-1) is an intracellular antioxid...

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Bibliografiske detaljer
Main Authors: Lubos, Edith, Loscalzo, Joseph, Handy, Diane E.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159114/
https://ncbi.nlm.nih.gov/pubmed/21087145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2010.3586
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