Phencyclidine-induced Loss of Asymmetric Spine Synapses in Rodent Prefrontal Cortex is Reversed by Acute and Chronic Treatment with Olanzapine

Enduring cognitive deficits exist in schizophrenic patients, long-term abusers of phencyclidine (PCP), as well as in animal PCP models of schizophrenia. It has been suggested that cognitive performance and memory processes are coupled with remodeling of pyramidal dendritic spine synapses in prefront...

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Bibliographische Detailangaben
Hauptverfasser: Elsworth, John D, Morrow, Bret A, Hajszan, Tibor, Leranth, Csaba, Roth, Robert H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158322/
https://ncbi.nlm.nih.gov/pubmed/21677652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.96
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