Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency

NADPH-cytochrome P450 oxidoreductase (CYPOR) is essential for electron donation to microsomal cytochrome P450-mediated monooxygenation in such diverse physiological processes as drug metabolism (approximately 85–90% of therapeutic drugs), steroid biosynthesis, and bioactive metabolite production (vi...

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Detalhes bibliográficos
Main Authors: Xia, Chuanwu, Panda, Satya P., Marohnic, Christopher C., Martásek, Pavel, Masters, Bettie Sue, Kim, Jung-Ja P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158178/
https://ncbi.nlm.nih.gov/pubmed/21808038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106632108
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