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Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency
NADPH-cytochrome P450 oxidoreductase (CYPOR) is essential for electron donation to microsomal cytochrome P450-mediated monooxygenation in such diverse physiological processes as drug metabolism (approximately 85–90% of therapeutic drugs), steroid biosynthesis, and bioactive metabolite production (vi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158178/ https://ncbi.nlm.nih.gov/pubmed/21808038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106632108 |
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