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Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA

Mammalian mtDNA is packaged in DNA-protein complexes denoted mitochondrial nucleoids. The organization of the nucleoid is a very fundamental question in mitochondrial biology and will determine tissue segregation and transmission of mtDNA. We have used a combination of stimulated emission depletion...

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Bibliografische gegevens
Hoofdauteurs: Kukat, Christian, Wurm, Christian A., Spåhr, Henrik, Falkenberg, Maria, Larsson, Nils-Göran, Jakobs, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158146/
https://ncbi.nlm.nih.gov/pubmed/21808029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109263108
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