Differential Bone Marrow Homing Capacity of VLA-4 and CD38 High Expressing Chronic Lymphocytic Leukemia Cells

BACKGROUND: VLA-4 and CD38 predict a poor clinical outcome in chronic lymphocytic leukemia (CLL). We used CLL samples with discordant VLA-4/CD38 risk to address their individual roles in human bone marrow infiltration (BM), CLL cell homing to murine BM, and in supportive CLL cell-stromal cell intera...

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Main Authors: Brachtl, Gabriele, Sahakyan, Karine, Denk, Ursula, Girbl, Tamara, Alinger, Beate, Hofbauer, Sebastian W., Neureiter, Daniel, Hofbauer, Josefina Piñón, Egle, Alexander, Greil, Richard, Hartmann, Tanja Nicole
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158106/
https://ncbi.nlm.nih.gov/pubmed/21876768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023758
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