CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21

Homing to distinct lymphoid organs enables chronic lymphocytic leukemia (CLL) cells to receive pro-survival and proliferative signals. Cytogenetic aberrations can significantly affect CLL cell compartmentalization. Trisomy 12 (tri12) defines a CLL subgroup with specific clinical features and increas...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ganghammer, Sylvia, Hutterer, Evelyn, Hinterseer, Elisabeth, Brachtl, Gabriele, Asslaber, Daniela, Krenn, Peter William, Girbl, Tamara, Berghammer, Petra, Geisberger, Roland, Egle, Alexander, Zucchetto, Antonella, Kruschinski, Anna, Gattei, Valter, Chigaev, Alexandre, Greil, Richard, Hartmann, Tanja Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494922/
https://ncbi.nlm.nih.gov/pubmed/25895128
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