A Signature in HIV-1 Envelope Leader Peptide Associated with Transition from Acute to Chronic Infection Impacts Envelope Processing and Infectivity

Mucosal transmission of the human immunodeficiency virus (HIV) results in a bottleneck in viral genetic diversity. Gnanakaran and colleagues used a computational strategy to identify signature amino acids at particular positions in Envelope that were associated either with transmitted sequences samp...

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Autori principali: Asmal, Mohammed, Hellmann, Ina, Liu, Weimin, Keele, Brandon F., Perelson, Alan S., Bhattacharya, Tanmoy, Gnanakaran, S., Daniels, Marcus, Haynes, Barton F., Korber, Bette T., Hahn, Beatrice H., Shaw, George M., Letvin, Norman L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158090/
https://ncbi.nlm.nih.gov/pubmed/21876761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023673
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