Optimised and Rapid Pre-clinical Screening in the SOD1(G93A) Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

The human SOD1(G93A) transgenic mouse has been used extensively since its development in 1994 as a model for amyotrophic lateral sclerosis (ALS). In that time, a great many insights into the toxicity of mutant SOD1 have been gained using this and other mutant SOD transgenic mouse models. They all de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mead, Richard J., Bennett, Ellen J., Kennerley, Aneurin J., Sharp, Paul, Sunyach, Claire, Kasher, Paul, Berwick, Jason, Pettmann, Brigitte, Battaglia, Guiseppe, Azzouz, Mimoun, Grierson, Andrew, Shaw, Pamela J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158065/
https://ncbi.nlm.nih.gov/pubmed/21876739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023244
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
Llwytho...

Eitemau Tebyg