Optimised and Rapid Pre-clinical Screening in the SOD1(G93A) Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

The human SOD1(G93A) transgenic mouse has been used extensively since its development in 1994 as a model for amyotrophic lateral sclerosis (ALS). In that time, a great many insights into the toxicity of mutant SOD1 have been gained using this and other mutant SOD transgenic mouse models. They all de...

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Main Authors: Mead, Richard J., Bennett, Ellen J., Kennerley, Aneurin J., Sharp, Paul, Sunyach, Claire, Kasher, Paul, Berwick, Jason, Pettmann, Brigitte, Battaglia, Guiseppe, Azzouz, Mimoun, Grierson, Andrew, Shaw, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158065/
https://ncbi.nlm.nih.gov/pubmed/21876739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023244
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