An EMT–Driven Alternative Splicing Program Occurs in Human Breast Cancer and Modulates Cellular Phenotype

Epithelial-mesenchymal transition (EMT), a mechanism important for embryonic development, plays a critical role during malignant transformation. While much is known about transcriptional regulation of EMT, alternative splicing of several genes has also been correlated with EMT progression, but the e...

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Main Authors: Shapiro, Irina M., Cheng, Albert W., Flytzanis, Nicholas C., Balsamo, Michele, Condeelis, John S., Oktay, Maja H., Burge, Christopher B., Gertler, Frank B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158048/
https://ncbi.nlm.nih.gov/pubmed/21876675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002218
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