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Evolutionary Accessibility of Mutational Pathways
Functional effects of different mutations are known to combine to the total effect in highly nontrivial ways. For the trait under evolutionary selection (‘fitness’), measured values over all possible combinations of a set of mutations yield a fitness landscape that determines which mutational states...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158036/ https://ncbi.nlm.nih.gov/pubmed/21876664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002134 |
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