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Evolutionary Accessibility of Mutational Pathways

Functional effects of different mutations are known to combine to the total effect in highly nontrivial ways. For the trait under evolutionary selection (‘fitness’), measured values over all possible combinations of a set of mutations yield a fitness landscape that determines which mutational states...

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Bibliografische gegevens
Hoofdauteurs: Franke, Jasper, Klözer, Alexander, de Visser, J. Arjan G. M., Krug, Joachim
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158036/
https://ncbi.nlm.nih.gov/pubmed/21876664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002134
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