Llwytho...

Targeting the GD3 acetylation pathway selectively induces apoptosis in glioblastoma

The expression of ganglioside GD3, which plays crucial roles in normal brain development, decreases in adults but is upregulated in neoplastic cells, where it regulates tumor invasion and survival. Normally a buildup of GD3 induces apoptosis, but this does not occur in gliomas due to formation of 9-...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Birks, Suzanne M., Danquah, John Owusu, King, Linda, Vlasak, Reinhardt, Gorecki, Dariusz C., Pilkington, Geoffrey J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158019/
https://ncbi.nlm.nih.gov/pubmed/21807667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor108
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