Essential Role of Complement Mannose-Binding Lectin-Associated Serine Proteases-1/3 in the Murine Collagen Antibody-Induced Model of Inflammatory Arthritis

Gene-targeted mice deficient in the complement mannose-binding lectin-associated serine protease-1 and -3 (MASP1/3(−/−)) express only the zymogen of factor D (pro-factor D [pro-Df]), a necessary component of the alternative pathway (AP). We used the murine collagen Ab-induced arthritis (CAIA) model,...

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Main Authors: Banda, Nirmal K., Takahashi, Minoru, Levitt, Brandt, Glogowska, Magdalena, Nicholas, Jessica, Takahashi, Kazue, Stahl, Gregory L., Fujita, Teizo, Arend, William P., Holers, V. Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157645/
https://ncbi.nlm.nih.gov/pubmed/20870940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001564
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