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Eliminating SF-1 (NR5A1) Sumoylation In Vivo Results in Ectopic Hedgehog Signaling and Disruption of Endocrine Development
Sumoylation is generally considered a repressive mark for many transcription factors. However, the in vivo importance of sumoylation for any given substrate remains unclear and is questionable because the extent of sumoylation appears exceedingly low for most substrates. Here, we permanently elimina...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , , , |
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| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
2011
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157481/ https://ncbi.nlm.nih.gov/pubmed/21820362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.06.028 |
| ট্যাগগুলো: |
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