Decreased Recognition of SUMO-Sensitive Target Genes following Modification of SF-1 (NR5A1)

SUMO modification of nuclear receptors, including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to repress their transcriptional activity. We examined the functional and structural consequences of SF-1 sumoylation at two conserved lysines (Lys119 and Lys194) th...

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Detalhes bibliográficos
Main Authors: Campbell, Lioudmila A., Faivre, Emily J., Show, Matthew D., Ingraham, Jared G., Flinders, Jeremy, Gross, John D., Ingraham, Holly A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593425/
https://ncbi.nlm.nih.gov/pubmed/18838537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00103-08
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