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Decreased Recognition of SUMO-Sensitive Target Genes following Modification of SF-1 (NR5A1)
SUMO modification of nuclear receptors, including the constitutively active receptor steroidogenic factor 1 (SF-1; NR5A1), is proposed to repress their transcriptional activity. We examined the functional and structural consequences of SF-1 sumoylation at two conserved lysines (Lys119 and Lys194) th...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593425/ https://ncbi.nlm.nih.gov/pubmed/18838537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00103-08 |
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