A Booster Vaccine Expressing a Latency-Associated Antigen Augments BCG Induced Immunity and Confers Enhanced Protection against Tuberculosis

BACKGROUND: In spite of a consistent protection against tuberculosis (TB) in children, Mycobacterium bovis Bacille Calmette-Guerin (BCG) fails to provide adequate protection against the disease in adults as well as against reactivation of latent infections or exogenous reinfections. It has been spec...

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Bibliographic Details
Main Authors: Dey, Bappaditya, Jain, Ruchi, Gupta, Umesh D., Katoch, V. M., Ramanathan, V. D., Tyagi, Anil K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157374/
https://ncbi.nlm.nih.gov/pubmed/21858087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023360
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