Adjunctive immunotherapy with α-crystallin based DNA vaccination reduces Tuberculosis chemotherapy period in chronically infected mice

By employing modified Cornell model, we have evaluated the potential of adjunctive immunotherapy with DNA vaccines to shorten the tuberculosis chemotherapy period and reduce disease reactivation. We demonstrate that α-crystallin based DNA vaccine (DNAacr) significantly reduced the chemotherapy perio...

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Hlavní autoři: Chauhan, Priyanka, Jain, Ruchi, Dey, Bappaditya, Tyagi, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650662/
https://ncbi.nlm.nih.gov/pubmed/23660989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01821
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