Succinate Dehydrogenase Is a Direct Target of Sirtuin 3 Deacetylase Activity

BACKGROUND: Sirtuins (SIRT1-7) are a family of NAD-dependent deacetylases and/or ADP-ribosyltransferases that are involved in metabolism, stress responses and longevity. SIRT3 is localized to mitochondria, where it deacetylates and activates a number of enzymes involved in fuel oxidation and energy...

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Detalhes bibliográficos
Main Authors: Finley, Lydia W. S., Haas, Wilhelm, Desquiret-Dumas, Valérie, Wallace, Douglas C., Procaccio, Vincent, Gygi, Steven P., Haigis, Marcia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157345/
https://ncbi.nlm.nih.gov/pubmed/21858060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023295
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