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Sirtuin Regulation of Mitochondria - Energy Production, Apoptosis, and Signaling

Sirtuins are a highly conserved family of proteins whose activity can extend lifespan in model organisms such as yeast, worms, and flies. Mammals contain seven sirtuins (SIRT1-7) that modulate distinct metabolic and stress response pathways. Three sirtuins, SIRT3, SIRT4 and SIRT5, are located in the...

詳細記述

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書誌詳細
主要な著者: Verdin, Eric, Hirschey, Matthew D., Finley, Lydia W.S., Haigis, Marcia C.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992946/
https://ncbi.nlm.nih.gov/pubmed/20863707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2010.07.003
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