The Pathogenic Role of Cystathionine γ-Lyase/Hydrogen Sulfide in Streptozotocin-Induced Diabetes in Mice

Reduced β-cell mass and increased activities of ATP-sensitive K(+) channels in pancreatic β cells are associated with the pathogenesis of diabetes. Cystathionine γ-lyase (CSE) is a major hydrogen sulfide (H(2)S)–producing enzyme in pancreatic β cells. Herein, we examine the effects of genetic and ph...

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Bibliografiske detaljer
Main Authors: Yang, Guangdong, Tang, Guanghua, Zhang, Ling, Wu, Lingyun, Wang, Rui
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157274/
https://ncbi.nlm.nih.gov/pubmed/21718679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.04.028
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