Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S‐sulfhydration in ApoE‐knockout atherosclerotic mice

BACKGROUND AND PURPOSE: Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia. H(2)S also lowers serum homocysteine in rats with mild hyperhomocysteinemia, but the pharmacological mechanism is unknown. The present study investigated the mechanism(s) involved. EXPERIMENT...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Fan, Jinhui, Zheng, Fengjiao, Li, Shuangyue, Cui, Cangting, Jiang, Shan, Zhang, Jun, Cai, Jun, Cui, Qinghua, Yang, Jichun, Tang, Xinjing, Xu, Guoheng, Geng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692586/
https://ncbi.nlm.nih.gov/pubmed/31140595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14719
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