Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S‐sulfhydration in ApoE‐knockout atherosclerotic mice

BACKGROUND AND PURPOSE: Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia. H(2)S also lowers serum homocysteine in rats with mild hyperhomocysteinemia, but the pharmacological mechanism is unknown. The present study investigated the mechanism(s) involved. EXPERIMENT...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Fan, Jinhui, Zheng, Fengjiao, Li, Shuangyue, Cui, Cangting, Jiang, Shan, Zhang, Jun, Cai, Jun, Cui, Qinghua, Yang, Jichun, Tang, Xinjing, Xu, Guoheng, Geng, Bin
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692586/
https://ncbi.nlm.nih.gov/pubmed/31140595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14719
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