Hydrogen sulfide lowers hyperhomocysteinemia dependent on cystathionine γ lyase S‐sulfhydration in ApoE‐knockout atherosclerotic mice

BACKGROUND AND PURPOSE: Hydrogen sulfide donors can block the cardiovascular injury of hyperhomocysteinemia. H(2)S also lowers serum homocysteine in rats with mild hyperhomocysteinemia, but the pharmacological mechanism is unknown. The present study investigated the mechanism(s) involved. EXPERIMENT...

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Publicado en:Br J Pharmacol
Autores principales: Fan, Jinhui, Zheng, Fengjiao, Li, Shuangyue, Cui, Cangting, Jiang, Shan, Zhang, Jun, Cai, Jun, Cui, Qinghua, Yang, Jichun, Tang, Xinjing, Xu, Guoheng, Geng, Bin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692586/
https://ncbi.nlm.nih.gov/pubmed/31140595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14719
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