ERβ1 Represses FOXM1 Expression through Targeting ERα to Control Cell Proliferation in Breast Cancer

In this study, we investigated the effects of ectopic estrogen receptor (ER)β1 expression in breast cancer cell lines and nude mice xenografts and observed that ERβ1 expression suppresses tumor growth and represses FOXM1 mRNA and protein expression in ERα-positive but not ERα-negative breast cancer...

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Bibliographic Details
Main Authors: Horimoto, Yoshiya, Hartman, Johan, Millour, Julie, Pollock, Steven, Olmos, Yolanda, Ho, Ka-Kei, Coombes, R. Charles, Poutanen, Matti, Mäkelä, Sari I., El-Bahrawy, Mona, Speirs, Valerie, Lam, Eric W.-F.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2011
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157253/
https://ncbi.nlm.nih.gov/pubmed/21763263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.052
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