FOXM1 is a transcriptional target of ERα and has a critical role in breast cancer endocrine sensitivity and resistance

In this study we investigated the regulation of FOXM1 expression by estrogen receptor α (ERα) and its role in hormonal therapy and endocrine resistance. FOXM1 protein and mRNA expression was regulated by ER-ligands, including estrogen, tamoxifen (OHT), and fulvestrant (ICI182780; ICI) in breast carc...

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Hlavní autoři: Millour, Julie, Constantinidou, Demetra, Stavropoulou, Alexandra V., Wilson, Miranda S. C., Myatt, Stephen S., Kwok, Jimmy M.-M., Sivanandan, Kavitta, Coombes, R. Charles, Medema, René H., Hartman, Johan, Lykkesfeldt, Anne E., Lam, Eric W.-F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874720/
https://ncbi.nlm.nih.gov/pubmed/20208560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.47
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