ERβ1 Represses FOXM1 Expression through Targeting ERα to Control Cell Proliferation in Breast Cancer

In this study, we investigated the effects of ectopic estrogen receptor (ER)β1 expression in breast cancer cell lines and nude mice xenografts and observed that ERβ1 expression suppresses tumor growth and represses FOXM1 mRNA and protein expression in ERα-positive but not ERα-negative breast cancer...

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Autors principals: Horimoto, Yoshiya, Hartman, Johan, Millour, Julie, Pollock, Steven, Olmos, Yolanda, Ho, Ka-Kei, Coombes, R. Charles, Poutanen, Matti, Mäkelä, Sari I., El-Bahrawy, Mona, Speirs, Valerie, Lam, Eric W.-F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157253/
https://ncbi.nlm.nih.gov/pubmed/21763263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.052
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