ERβ1 Represses FOXM1 Expression through Targeting ERα to Control Cell Proliferation in Breast Cancer

In this study, we investigated the effects of ectopic estrogen receptor (ER)β1 expression in breast cancer cell lines and nude mice xenografts and observed that ERβ1 expression suppresses tumor growth and represses FOXM1 mRNA and protein expression in ERα-positive but not ERα-negative breast cancer...

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Hlavní autoři: Horimoto, Yoshiya, Hartman, Johan, Millour, Julie, Pollock, Steven, Olmos, Yolanda, Ho, Ka-Kei, Coombes, R. Charles, Poutanen, Matti, Mäkelä, Sari I., El-Bahrawy, Mona, Speirs, Valerie, Lam, Eric W.-F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2011
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157253/
https://ncbi.nlm.nih.gov/pubmed/21763263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.052
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