ERβ1 Represses FOXM1 Expression through Targeting ERα to Control Cell Proliferation in Breast Cancer

In this study, we investigated the effects of ectopic estrogen receptor (ER)β1 expression in breast cancer cell lines and nude mice xenografts and observed that ERβ1 expression suppresses tumor growth and represses FOXM1 mRNA and protein expression in ERα-positive but not ERα-negative breast cancer...

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Detalhes bibliográficos
Main Authors: Horimoto, Yoshiya, Hartman, Johan, Millour, Julie, Pollock, Steven, Olmos, Yolanda, Ho, Ka-Kei, Coombes, R. Charles, Poutanen, Matti, Mäkelä, Sari I., El-Bahrawy, Mona, Speirs, Valerie, Lam, Eric W.-F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157253/
https://ncbi.nlm.nih.gov/pubmed/21763263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.052
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