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IMPAIRED cAMP-MEDIATED SIGNALING IN IEX-1-DEFICIENT VASCULAR SMOOTH MUSCLE CELLS

Gene-targeted deletion of the immediate early responsive gene X-1 (IEX-1) results in a significant increase in systemic arterial hypertension, but the underlying mechanism is not understood. Studies of arterial reactivity in isolated aortas revealed normal endothelium-dependent and independent vasor...

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Detalhes bibliográficos
Main Authors: Shahid, Mohd, Shen, Li, Seldin, David C., Lu, Bao, Ustyugova, Irina V., Chen, Xinyuan, Zapol, Warren M., Wu, Mei X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157252/
https://ncbi.nlm.nih.gov/pubmed/20713914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.154880
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