Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis

Aberrantly hyperactivated STAT3 has been found in human liver cancers as an oncogene; however, STAT3 has also been shown to exert hepatoprotective effects during liver injury. The balancing act that STAT3 plays between hepatoprotection and liver tumorigenesis remains poorly defined. In this study, t...

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Main Authors: Wang, Hua, Lafdil, Fouad, Wang, Lei, Park, Ogyi, Yin, Shi, Niu, Junyang, Miller, Andrew M., Sun, Zhaoli, Gao, Bin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157203/
https://ncbi.nlm.nih.gov/pubmed/21684247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.005
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