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Inflammation-associated IL-6/STAT3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in IL-10 deficient mice

Alcoholic and nonalcoholic steatohepatitis are characterized by fatty liver plus inflammation. It is generally believed that steatosis promotes inflammation, while inflammation in turn aggregates steatosis. Thus, we hypothesized the deletion of interleukin-10 (IL-10), a key anti-inflammatory cytokin...

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Detalhes bibliográficos
Main Authors: Miller, Andrew M., Wang, Hua, Bertola, Adeline, Park, Ogyi, Horiguchi, Norio, Ki, Sung Hwan, Yin, Shi, Lafdil, Fouad, Gao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197882/
https://ncbi.nlm.nih.gov/pubmed/21725996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24517
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