Anti-inflammatory and anti-apoptotic roles of endothelial cell STAT3 in alcoholic liver injury

BACKGROUND: It is generally believed that the hepatoprotective effect of interleukin-6 (IL-6) is mediated via activation of signal transducer and activator of transcription 3 (STAT3) in hepatocytes. IL-6-deficient mice are more susceptible to alcohol-induced hepatocyte apoptosis and steatosis and el...

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Main Authors: Miller, Andrew M, Wang, Hua, Park, Ogyi, Horiguchi, Norio, Lafdil, Fouad, Mukhopadhyay, Partha, Moh, Akira, Fu, Xin Yuan, Kunos, George, Pacher, Pal, Gao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858250/
https://ncbi.nlm.nih.gov/pubmed/20102572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2009.01141.x
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