Tissue inhibitor of metalloproteinase 1 (TIMP-1) deficiency exacerbates carbon tetrachloride-induced liver injury and fibrosis in mice: involvement of hepatocyte STAT3 in TIMP-1 production

BACKGROUND: Tissue inhibitor of metalloproteinase 1 (TIMP-1), which is thought to be produced mainly by activated hepatic stellate cells and Kupffer cells in the liver, plays a pivotal role in matrix remodeling during liver injury and repair; while the effect of TIMP-1 on hepatocellular damage remai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wang, Hua, Lafdil, Fouad, Wang, Lei, Yin, Shi, Feng, Dechun, Gao, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125204/
https://ncbi.nlm.nih.gov/pubmed/21711826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-14
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados