Tissue inhibitor of metalloproteinase 1 (TIMP-1) deficiency exacerbates carbon tetrachloride-induced liver injury and fibrosis in mice: involvement of hepatocyte STAT3 in TIMP-1 production

BACKGROUND: Tissue inhibitor of metalloproteinase 1 (TIMP-1), which is thought to be produced mainly by activated hepatic stellate cells and Kupffer cells in the liver, plays a pivotal role in matrix remodeling during liver injury and repair; while the effect of TIMP-1 on hepatocellular damage remai...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wang, Hua, Lafdil, Fouad, Wang, Lei, Yin, Shi, Feng, Dechun, Gao, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125204/
https://ncbi.nlm.nih.gov/pubmed/21711826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-14
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky