Evaluation of (111)In-Labeled Cyclic RGD Peptides: Effects of Peptide and Linker Multiplicity on Their Tumor Uptake, Excretion Kinetics and Metabolic Stability

Purpose: The purpose of this study was to demonstrate the valence of cyclic RGD peptides, P-RGD (PEG(4)-c(RGDfK): PEG(4) = 15-amino-4,710,13-tetraoxapentadecanoic acid), P-RGD(2) (PEG(4)-E[c(RGDfK)](2), 2P-RGD(4) (E{PEG(4)-E[c(RGDfK)](2)}(2), 2P4G-RGD(4) (E{PEG(4)-E[G(3)-c(RGDfK)](2)}(2): G(3) = Gly...

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Detalhes bibliográficos
Main Authors: Shi, Jiyun, Zhou, Yang, Chakraborty, Sudipta, Kim, Young-Seung, Jia, Bing, Wang, Fan, Liu, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2011
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157017/
https://ncbi.nlm.nih.gov/pubmed/21850213
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