Improving Tumor Uptake and Pharmacokinetics of (64)Cu-Labeled Cyclic RGD Peptide Dimers with Gly(3) and PEG(4) Linkers

Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides represent a new class of radiotracers with potential for the early tumor detection and non-invasive monitoring of tumor metastasis and therapeutic response in cancer patients. This report describes the synthesis of two cyclic RGD peptide dimer conjugate...

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Bibliographic Details
Main Authors: Shi, Jiyun, Kim, Young-Seung, Zhai, Shizhen, Liu, Zhaofei, Chen, Xiaoyuan, Liu, Shuang
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676896/
https://ncbi.nlm.nih.gov/pubmed/19320477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800455p
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