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Receptor protein tyrosine phosphatases are novel components of a polycystin complex
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutation of PKD1 and PKD2 that encode polycystin-1 and polycystin-2. Polycystin-1 is tyrosine phosphorylated and modulates multiple signaling pathways including AP-1, but the identity of the phosphatases regulating polycystin-1 are pr...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156852/ https://ncbi.nlm.nih.gov/pubmed/21126580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.11.006 |
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