Receptor protein tyrosine phosphatases are novel components of a polycystin complex

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutation of PKD1 and PKD2 that encode polycystin-1 and polycystin-2. Polycystin-1 is tyrosine phosphorylated and modulates multiple signaling pathways including AP-1, but the identity of the phosphatases regulating polycystin-1 are pr...

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Bibliographic Details
Main Authors: Boucher, Catherine A., Ward, Heather H., Case, Ruth L., Thurston, Katie S., Li, Xiaohong, Needham, Andrew, Romero, Elsa, Hyink, Deborah, Qamar, Seema, Roitbak, Tamara, Powell, Samantha, Ward, Christopher, Wilson, Patricia D., Wandinger-Ness, Angela, Sandford, Richard N.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156852/
https://ncbi.nlm.nih.gov/pubmed/21126580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.11.006
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