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Suppression of Glypican 3 Inhibits Growth of Hepatocellular Carcinoma Cells through Up-Regulation of TGF-β2

Glypican 3 (GPC3) is a valuable diagnostic marker and a potential therapeutic target in hepatocellular carcinoma (HCC). To evaluate the efficacy of targeting GPC3 at the translational level, we used RNA interference to examine the biologic and molecular effects of GPC3 suppression in HCC cells in vi...

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書誌詳細
主要な著者: Sun, Chris K, Chua, Mei-Sze, He, Jing, So, Samuel K
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press Inc. 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156664/
https://ncbi.nlm.nih.gov/pubmed/21847365
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