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Suppression of ATAD2 inhibits hepatocellular carcinoma progression through activation of p53- and p38-mediated apoptotic signaling

The ATPase family, AAA domain containing 2 (ATAD2) is highly expressed in multiple cancers. We aim to understand the clinical and biological significance of ATAD2 over-expression in hepatocellular carcinoma (HCC), as a means to validate it as a therapeutic target in HCC. We demonstrated that ATAD2 w...

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發表在:Oncotarget
Main Authors: Lu, Wen-Jing, Chua, Mei-Sze, So, Samuel K.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747184/
https://ncbi.nlm.nih.gov/pubmed/26497681
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