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Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most lethal malignancy worldwide with no curative therapies. To discover potentially novel therapeutic targets for HCC, we previously studied the gene expression profiles of HCC patients and identified that significant upregulation of N-Myc downstream regu...

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Bibliografiske detaljer
Udgivet i:Carcinogenesis
Main Authors: Lu, Wen-Jing, Chua, Mei-Sze, So, Samuel K.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335260/
https://ncbi.nlm.nih.gov/pubmed/24302615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt401
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