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Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most lethal malignancy worldwide with no curative therapies. To discover potentially novel therapeutic targets for HCC, we previously studied the gene expression profiles of HCC patients and identified that significant upregulation of N-Myc downstream regu...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Lu, Wen-Jing, Chua, Mei-Sze, So, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335260/
https://ncbi.nlm.nih.gov/pubmed/24302615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt401
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