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Suppressing N-Myc downstream regulated gene 1 reactivates senescence signaling and inhibits tumor growth in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the fifth most lethal malignancy worldwide with no curative therapies. To discover potentially novel therapeutic targets for HCC, we previously studied the gene expression profiles of HCC patients and identified that significant upregulation of N-Myc downstream regu...

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Bibliografske podrobnosti
izdano v:Carcinogenesis
Main Authors: Lu, Wen-Jing, Chua, Mei-Sze, So, Samuel K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335260/
https://ncbi.nlm.nih.gov/pubmed/24302615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt401
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