Suppression of Glypican 3 Inhibits Growth of Hepatocellular Carcinoma Cells through Up-Regulation of TGF-β2

Glypican 3 (GPC3) is a valuable diagnostic marker and a potential therapeutic target in hepatocellular carcinoma (HCC). To evaluate the efficacy of targeting GPC3 at the translational level, we used RNA interference to examine the biologic and molecular effects of GPC3 suppression in HCC cells in vi...

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Bibliographic Details
Main Authors: Sun, Chris K, Chua, Mei-Sze, He, Jing, So, Samuel K
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2011
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156664/
https://ncbi.nlm.nih.gov/pubmed/21847365
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