Identification of Oncogenic Point Mutations and Hyperphosphorylation of Anaplastic Lymphoma Kinase in Lung Cancer

The oncogenic property of anaplastic lymphoma kinase (ALK) plays an essential role in the pathogenesis of various cancers and serves as an important therapeutic target. In this study, we identified frequent intragenic loss of heterozygosity and six novel driver mutations within ALK in lung adenocarc...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yi-Wei, Tu, Pang-Hsien, Lin, Kuen-Tyng, Lin, Shu-Chen, Ko, Jenq-Yuh, Jou, Yuh-Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156661/
https://ncbi.nlm.nih.gov/pubmed/21847362
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