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Effects of Kappa Opioids in An Assay of Pain-Depressed Intracranial Self-Stimulation in Rats
RATIONALE: Selective, centrally acting kappa opioid agonists produce antinociception in a wide range of preclinical assays, but these compounds perform poorly as analgesics in humans. This discrepancy may be related to the behavioral depressant effects of kappa agonists. Kappa antagonists do not typ...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156454/ https://ncbi.nlm.nih.gov/pubmed/20101391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-009-1770-6 |
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