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Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model

The increasing use of the anti-microbial triclocarban (TCC) in personal care products (PCPs) has resulted in concern regarding environmental pollution. TCC is a potent inhibitor of soluble epoxide hydrolase (sEH). Inhibitors of sEH (sEHIs) are anti-inflammatory, anti-hypertensive and cardio-protecti...

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Bibliographic Details
Main Authors: Liu, Jun-Yan, Qiu, Hong, Morisseau, Christophe, Hwang, Sung Hee, Tsai, Hsing-Ju, Ulu, Arzu, Chiamvimonvat, Nipavan, Hammock, Bruce D
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156297/
https://ncbi.nlm.nih.gov/pubmed/21741984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.06.017
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