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Multiphoton ANS fluorescence microscopy as an in vivo sensor for protein misfolding stress

The inability of cells to maintain protein folding homeostasis is implicated in the development of neurodegenerative diseases, malignant transformation, and aging. We find that multiphoton fluorescence imaging of 1-anilinonaphthalene-8-sulfonate (ANS) can be used to assess cellular responses to prot...

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Autori principali: Hadley, Kevin C., Borrelli, Michael J., Lepock, James R., McLaurin, JoAnne, Croul, Sidney E., Guha, Abhijit, Chakrabartty, Avijit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156256/
https://ncbi.nlm.nih.gov/pubmed/21484286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-011-0266-6
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