Učitavanje...
Engineering hepatocyte growth factor fragments with high stability and activity as Met receptor agonists and antagonists
The Met receptor tyrosine kinase and its ligand hepatocyte growth factor (HGF) play an important role in mediating both tumor progression and tissue regeneration. The N-terminal and first Kringle domains (NK1) of HGF comprise a naturally occurring splice variant that retains the ability to activate...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156163/ https://ncbi.nlm.nih.gov/pubmed/21788476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102561108 |
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