VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting

Although our understanding of the molecular regulation of adult neovascularization has advanced tremendously, vascular-targeted therapies for tissue ischemia remain suboptimal. The master regulatory transcription factors of the hypoxia-inducible factor (HIF) family are attractive therapeutic targets...

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Bibliographic Details
Main Authors: Oladipupo, Sunday, Hu, Song, Kovalski, Joanna, Yao, Junjie, Santeford, Andrea, Sohn, Rebecca E., Shohet, Ralph, Maslov, Konstantin, Wang, Lihong V., Arbeit, Jeffrey M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156154/
https://ncbi.nlm.nih.gov/pubmed/21784979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101321108
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