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VEGF is essential for hypoxia-inducible factor-mediated neovascularization but dispensable for endothelial sprouting
Although our understanding of the molecular regulation of adult neovascularization has advanced tremendously, vascular-targeted therapies for tissue ischemia remain suboptimal. The master regulatory transcription factors of the hypoxia-inducible factor (HIF) family are attractive therapeutic targets...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156154/ https://ncbi.nlm.nih.gov/pubmed/21784979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101321108 |
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